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この半世紀において,わが国の肺癌による死亡数・死亡率の急増は著しいものがある.1998年にその死亡数は5万人をこえ,わが国の悪性腫瘍による死亡数の第1位にあった胃癌を凌駕した.およそ半世紀の間に肺癌死亡数・死亡率の急増は喫煙量と喫煙率の急激な増加に平行して認められ,疫学的に喫煙が肺癌発生の最大の危険因子として認識されてきた.疫学的統計では5歳階級別肺癌死亡率の観察で5歳階級ごとに死亡率の傾向が異なり,出生年別肺癌死亡率の推移において出生コホート効果が認められた.第二次世界大戦直後に当時の10代は極端なタバコ不足の時代を過ごした.この生涯喫煙率の低い年齢層(現在の60歳代)では男女で死亡数・死亡率の増加が抑えられた.タバコ消費量と喫煙率の減少が肺癌発生を抑制したと考えられている.年齢調整肺癌死亡率,年齢階級別肺癌死亡率・死亡数の推移を観察すると肺癌になりやすい高齢者が増加する高齢化社会も肺癌が増加する大きな要因であることが認められた.

In the past five decades, the number of deaths and mortality rates of lung cancer in Japan have increased dramatically. In 1998, the number of deaths exceeded 50,000, surpassing that of gastric cancer which was the leading cause of death from malignant tumors in Japan. The rapid increase in the number of deaths and mortality rates of lung cancer in the past five decades was in parallel with that in the amount of smoking and smoking prevalence. Smoking was epidemiologically identified as the leading risk factor for lung cancer. Regarding the epidemiological statistics, the lung cancer mortality rates by 5-year age group revealed that the trends in mortality rates vary by age group. Birth cohort effect was observed in the trends in lung cancer mortality rates by year of birth. Immediately after World War II, teenagers in those days survived time when cigarettes were extremely scarce. In this age group (now in their 60's) with a low prevalence of ever-smoking, the increase in the number of deaths and mortality rates of lung cancer was reduced in both males and females. Reduction in cigarette consumption and smoking prevalence seems to have reduced the incidence of lung cancer. Trends in age-adjusted lung cancer mortality rates and the lung cancer mortality rates and number of deaths by age group show that smoking is the leading risk factor contributing to increased incidence of lung cancer in this aging society with an increasing number of the elderly with a high risk of lung cancer.

In the past five decades, the number of deaths and mortality rates of lung cancer in Japan have increased dramatically. In 1998, the number of deaths exceeded 50,000, surpassing that of gastric cancer which was the leading cause of death from malignant tumors in Japan. The rapid increase in the number of deaths and mortality rates of lung cancer in the past five decades was in parallel with that in the amount of smoking and smoking prevalence. Smoking was epidemiologically identified as the leading risk factor for lung cancer. Regarding the epidemiological statistics,Epidemiological analysis of the lung cancer mortality rates by 5-year age group revealed that the trends in mortality rates vary by age group. BirthIn addition, birth cohort effect was observed in theeffects on trends in lung cancer mortality rates by year of birth were observed. Immediately after World War II, teenagers in those days survived time when cigarettes were extremely scarce. In this age group (now in their 60's) with a low prevalence of ever-smoking, the increase in the number of deaths and mortality rates of lung cancer was reducedwere low in both males and females. Reduction in cigarette consumption and smoking prevalence seems to have reduced the incidence of lung cancer. Trends in age-adjusted lung cancer mortality rates and the lung cancer mortality rates and number of deaths by age group show thatidentified smoking isas the leading risk factor contributing to increased incidence of lung cancer in this aging society with an increasing number of the elderly with a high risk of lung cancer.

In Japan, In the past five decades, the the number of deaths and mortality rates of due to lung cancer in Japan have increased dramatically in the past 5 decades, with. In 1998, the number of deaths due to lung cancer exceeding ed 50,000 in 1998;, this was surpassing higher than that the number of deaths of due to gastric cancer, which was the leading cause of death from due to malignant tumors in Japan. The rapid increase in the number of deaths and mortality rates of due to lung cancer in the past five 5 decades was is in parallel with that the increase in the amount of cigarette consumption smoking and smoking prevalence. Smoking was has been epidemiologically identified as the leading risk factor for lung cancer. Moreover, Eepidemiological analysis of the lung cancer mortality rates by 5-year age groups revealed that the trends in mortality rates vary by age group. In addition, birth cohort effects of the birth cohort on the trends in lung cancer mortality rates due to lung cancer by year of birth were observed by year of birth. Immediately after World War II, Teenagers teenagers in those days in the days immediately after World War II lived in a time when survived time when cigarettes were extremely scarce. In this age group (now currently in their 60's), which with  has a low prevalence of ever-smoking, the number of deaths and mortality rates of due to lung cancer were low in both males men and femaleswomen. The Rreduction in cigarette consumption and smoking prevalence seems to have reduced the incidence of lung cancer. Thus,T trends in mortality rates and age-adjusted lung cancer mortality rates due to lung cancer and the lung cancer mortality rates and as well as the number of deaths by age group identified revealed smoking as to be the leading risk factor that contributed ing to the increased incidence of lung cancer in this aging society; also, with an increasing number of the elderly individuals with were at a high risk of lung cancer.

In Japan, In the past five decades, the the number of deaths from lung cancer and its mortality rates of lung cancer in Japan have increased dramatically over the past 5 decades, with. In 1998, the number of deaths from lung cancer exceeding ed 50,000 in 1998;, this was surpassing higher than that the number of deaths of from gastric cancer, which was the leading cause of death from malignant tumors in Japan. Thise rapid increase in the number of deaths from lung cancer and its mortality rates of lung cancer in the past five decades was in parallel with parallels that the increase in cigarette consumptionthe amount of smoking and smoking prevalence. Smoking was has been epidemiologically identified as the leading risk factor for lung cancer. Moreover, Eepidemiological analysis of the lung cancer mortality rates by 5-year age groups revealed that the trends in mortality rates vary by age group. In addition, birth cohort effects of the birth cohort on the trends in lung cancer mortality rates by year of birth were observed by year of birth. Immediately after World War II, Teenagers teenagers in those days in the days immediately after World War II lived in a time when cigarettes were extremely scarcesurvived time when cigarettes were extremely scarce. In this age group (now currently in their 60's), which  with has a low prevalence of ever-smoking, the number of deaths from lung cancer and its mortality rates of lung cancer were low in both males men and femaleswomen. The Rreduction in cigarette consumption and smoking prevalence seems to have reduced the incidence of lung cancer. Thus,T trends in mortality rates and age-adjusted lung cancer mortality rates of lung cancer and the lung cancer mortality rates and  the number of deaths from lung cancer by age group identified smoking as the leading risk factor contributing  to the increased incidence of lung cancer in this aging society; moreover, with an increasing number of the elderly individuals with were at a high risk of lung cancer.

この半世紀において,わが国の肺癌による死亡数・死亡率の急増は著しいものがある.1998年にその死亡数は5万人をこえ,わが国の悪性腫瘍による死亡数の第1位にあった胃癌を凌駕した.およそ半世紀の間に肺癌死亡数・死亡率の急増は喫煙量と喫煙率の急激な増加に平行して認められ,疫学的に喫煙が肺癌発生の最大の危険因子として認識されてきた.疫学的統計では5歳階級別肺癌死亡率の観察で5歳階級ごとに死亡率の傾向が異なり,出生年別肺癌死亡率の推移において出生コホート効果が認められた.第二次世界大戦直後に当時の10代は極端なタバコ不足の時代を過ごした.この生涯喫煙率の低い年齢層(現在の60歳代)では男女で死亡数・死亡率の増加が抑えられた.タバコ消費量と喫煙率の減少が肺癌発生を抑制したと考えられている.年齢調整肺癌死亡率,年齢階級別肺癌死亡率・死亡数の推移を観察すると肺癌になりやすい高齢者が増加する高齢化社会も肺癌が増加する大きな要因であることが認められた.

In the past five decades, the number of deaths and mortality rates of lung cancer in Japan have increased dramatically. In 1998, the number of deaths exceeded 50,000, surpassing that of gastric cancer which was the leading cause of death from malignant tumors in Japan. The rapid increase in the number of deaths and mortality rates of lung cancer in the past five decades was in parallel with that in the amount of smoking and smoking prevalence. Smoking was epidemiologically identified as the leading risk factor for lung cancer. Regarding the epidemiological statistics, the lung cancer mortality rates by 5-year age group revealed that the trends in mortality rates vary by age group. Birth cohort effect was observed in the trends in lung cancer mortality rates by year of birth. Immediately after World War II, teenagers in those days survived time when cigarettes were extremely scarce. In this age group (now in their 60's) with a low prevalence of ever-smoking, the increase in the number of deaths and mortality rates of lung cancer was reduced in both males and females. Reduction in cigarette consumption and smoking prevalence seems to have reduced the incidence of lung cancer. Trends in age-adjusted lung cancer mortality rates and the lung cancer mortality rates and number of deaths by age group show that smoking is the leading risk factor contributing to increased incidence of lung cancer in this aging society with an increasing number of the elderly with a high risk of lung cancer.

In the past five 5 decades in Japan, the number of deaths from lung cancer and its mortality rates of lung cancer in Japan have increased dramatically. In 1998, the number of deaths from lung cancer exceeded 50,000, surpassing that fromof gastric cancer, which was the leading cause of death from malignant tumors in Japan. The rapid increase in the number of deaths from lung cancer and its mortality rates of lung cancer in the past five 5 decades was in parallels  with that the increase in cigarette consumptionthe amount of smoking and smoking prevalence. Smoking was epidemiologically identified as the leading risk factor for lung cancer. Epidemiological analysis of the lung cancer mortality rates by 5-year age groups revealed that the trends in mortality rates vary by age group. In addition, birth cohort effects of birth cohort on the trends in lung cancer mortality rates by year of birth were observed by year of birth. Immediately after World War II, teenagers Teenagers in those the days immediately after World War II lived in a time when cigarettes were extremely scarcesurvived time when cigarettes were extremely scarce. In this age group (now currently in their 60's), which  with has a low prevalence of ever-smoking, the number of deaths from lung cancer and its mortality rates of lung cancer were low in both males men and femaleswomen. Reduction in cigarette consumption and smoking prevalence seems to have reduced the incidence of lung cancer. Trends in mortality rates and age-adjusted lung cancer mortality rates of lung cancer  and the lung cancer mortality rates and and the number of deaths from lung cancer by age group identified smoking as the leading risk factor contributing to the increased incidence of lung cancer in this aging society, with an increasing number of the elderly individuals with being at a high risk of lung cancer.

In the past five 5 decades, the number of deaths and mortality rates of due to lung cancer in Japan have increased dramatically. In 1998, the number of deaths due to lung cancer exceeded 50,000, surpassing that of gastric cancer, which was the leading cause of death from due to malignant tumors in Japan. The rapid increase in the number of deaths and mortality rates of due to lung cancer in the past five 5 decades was is in parallel with that the increase in the amount of smoking and smoking prevalence. Smoking was epidemiologically identified as the leading risk factor for lung cancer. Epidemiological analysis of the lung cancer mortality rates by 5-year age groups revealed that the trends in mortality rates vary by age group. In addition, birth cohort effects of birth cohort on the trends in lung cancer mortality rates by year of birth were observed by year of birth. Immediately after World War II, teenagers Teenagers in those the days immediately after World War II survived time lived in a time when cigarettes were extremely scarce. In this age group (now currently in their 60's), which  with has a low prevalence of ever-smoking, the number of deaths and mortality rates of due to lung cancer were low in both males men and femaleswomen. Reduction in cigarette consumption and smoking prevalence seems to have reduced the incidence of lung cancer. Trends in age-adjusted lung cancer mortality rates and the lung cancer mortality rates and as well as the number of deaths by age group identified revealed smoking as to be the leading risk factor contributing to the increased incidence of lung cancer in this aging society, with an increasing number of the elderly individuals with being at a high risk of lung cancer.

In the past five 5 decades in Japan, the number of deaths from lung cancer and its mortality rates of lung cancer in Japan have increased dramatically. In 1998, the number of deaths from lung cancer exceeded 50,000, surpassing that fromof gastric cancer, which was the leading cause of death from malignant tumors in Japan. The rapid increase in the number of deaths from lung cancer and its mortality rates of lung cancer in the past five 5 decades was in parallels  with that the increase in cigarette consumptionthe amount of smoking and smoking prevalence. Smoking was epidemiologically identified as the leading risk factor for lung cancer. Epidemiological analysis of the lung cancer mortality rates by 5-year age groups revealed that the trends in mortality rates vary by age group. In addition, birth cohort effects of birth cohort on the trends in lung cancer mortality rates by year of birth were observed by year of birth. Immediately after World War II, teenagers Teenagers in those the days immediately after World War II lived in a time when cigarettes were extremely scarcesurvived time when cigarettes were extremely scarce. In this age group (now currently in their 60's), which  with has a low prevalence of ever-smoking, the number of deaths from lung cancer and its mortality rates of lung cancer were low in both males men and femaleswomen. Reduction in cigarette consumption and smoking prevalence seems to have reduced the incidence of lung cancer. Trends in mortality rates and age-adjusted lung cancer mortality rates of lung cancer  and the lung cancer mortality rates and and the number of deaths from lung cancer by age group identified smoking as the leading risk factor contributing to the increased incidence of lung cancer in this aging society, with an increasing number of the elderly individuals with being at a high risk of lung cancer.

この半世紀において,わが国の肺癌による死亡数・死亡率の急増は著しいものがある.1998年にその死亡数は5万人をこえ,わが国の悪性腫瘍による死亡数の第1位にあった胃癌を凌駕した.およそ半世紀の間に肺癌死亡数・死亡率の急増は喫煙量と喫煙率の急激な増加に平行して認められ,疫学的に喫煙が肺癌発生の最大の危険因子として認識されてきた.疫学的統計では5歳階級別肺癌死亡率の観察で5歳階級ごとに死亡率の傾向が異なり,出生年別肺癌死亡率の推移において出生コホート効果が認められた.第二次世界大戦直後に当時の10代は極端なタバコ不足の時代を過ごした.この生涯喫煙率の低い年齢層(現在の60歳代)では男女で死亡数・死亡率の増加が抑えられた.タバコ消費量と喫煙率の減少が肺癌発生を抑制したと考えられている.年齢調整肺癌死亡率,年齢階級別肺癌死亡率・死亡数の推移を観察すると肺癌になりやすい高齢者が増加する高齢化社会も肺癌が増加する大きな要因であることが認められた.

In the past five decades, the number of deaths and mortality rates of lung cancer in Japan have increased dramatically. In 1998, the number of deaths exceeded 50,000, surpassing that of gastric cancer which was the leading cause of death from malignant tumors in Japan. The rapid increase in the number of deaths and mortality rates of lung cancer in the past five decades was in parallel with that in the amount of smoking and smoking prevalence. Smoking was epidemiologically identified as the leading risk factor for lung cancer. Regarding the epidemiological statistics, the lung cancer mortality rates by 5-year age group revealed that the trends in mortality rates vary by age group. Birth cohort effect was observed in the trends in lung cancer mortality rates by year of birth. Immediately after World War II, teenagers in those days survived time when cigarettes were extremely scarce. In this age group (now in their 60's) with a low prevalence of ever-smoking, the increase in the number of deaths and mortality rates of lung cancer was reduced in both males and females. Reduction in cigarette consumption and smoking prevalence seems to have reduced the incidence of lung cancer. Trends in age-adjusted lung cancer mortality rates and the lung cancer mortality rates and number of deaths by age group show that smoking is the leading risk factor contributing to increased incidence of lung cancer in this aging society with an increasing number of the elderly with a high risk of lung cancer.

In the past five decades, the number of deaths and mortality rates of lung cancer in Japan have increased dramatically. In 1998, the number of deaths exceeded 50,000, surpassing that of gastric cancer which was the leading cause of death from malignant tumors in Japan. The rapid increase in the number of deaths and mortality rates of lung cancer in the past five decades was in parallel with that in the amount of smoking and smoking prevalence. Smoking was epidemiologically identified as the leading risk factor for lung cancer. Regarding the epidemiological statistics,Epidemiological analysis of the lung cancer mortality rates by 5-year age group revealed that the trends in mortality rates vary by age group. BirthIn addition, birth cohort effect was observed in theeffects on trends in lung cancer mortality rates by year of birth were observed. Immediately after World War II, teenagers in those days survived time when cigarettes were extremely scarce. In this age group (now in their 60's) with a low prevalence of ever-smoking, the increase in the number of deaths and mortality rates of lung cancer was reducedwere low in both males and females. Reduction in cigarette consumption and smoking prevalence seems to have reduced the incidence of lung cancer. Trends in age-adjusted lung cancer mortality rates and the lung cancer mortality rates and number of deaths by age group show thatidentified smoking isas the leading risk factor contributing to increased incidence of lung cancer in this aging society with an increasing number of the elderly with a high risk of lung cancer.

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